Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens MYC associated factor X (MAX), transcript variant 3 (NM_145113). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P61244 |
| Entry Name | MAX_HUMAN |
| Gene Names | MAX BHLHD4 |
| Alternative Gene Names | BHLHD4 |
| Alternative Protein Names | Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 160 |
| Molecular Weight(Da) | 18275 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS |
Background
| Function | FUNCTION: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements. {ECO:0000269|PubMed:26070438}. |
| Pathway | |
| Protein Families | MAX family |
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |